Detalhe da pesquisa
1.
Physiologically based pharmacokinetic modeling to predict the impact of liver cirrhosis on glucuronidation via UGT1A4 & UGT2B7/2B4 - a case study with midazolam.
Drug Metab Dispos
; 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38653501
2.
The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes.
PLoS Pathog
; 17(3): e1009382, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730100
3.
Rats with Long-Term Cholestasis Have a Decreased Cytosolic but Maintained Mitochondrial Hepatic CoA Pool.
Int J Mol Sci
; 24(5)2023 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36901795
4.
Cytochrome P450 1A2 is the most important enzyme for hepatic metabolism of the metamizole metabolite 4-methylaminoantipyrine.
Br J Clin Pharmacol
; 88(4): 1885-1896, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34648192
5.
Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line.
Int J Mol Sci
; 23(4)2022 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216404
6.
PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle.
Int J Mol Sci
; 23(20)2022 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36293168
7.
The Risk of Muscular Events Among New Users of Hydrophilic and Lipophilic Statins: an Observational Cohort Study.
J Gen Intern Med
; 36(9): 2639-2647, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33751411
8.
Effect of deglucuronidation on the results of the Basel phenotyping cocktail.
Br J Clin Pharmacol
; 87(12): 4608-4618, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33890704
9.
Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans.
Br J Clin Pharmacol
; 87(3): 1466-1474, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32959922
10.
Antiseizure drugs and risk of developing smoking-related chronic obstructive pulmonary disease or lung cancer: A population-based case-control study.
Br J Clin Pharmacol
; 87(3): 1253-1263, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738070
11.
Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression.
Int J Mol Sci
; 22(9)2021 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34066911
12.
Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation.
Int J Mol Sci
; 22(18)2021 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34575957
13.
The effect of food on the pharmacokinetics of oral ivermectin.
J Antimicrob Chemother
; 75(2): 438-440, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691813
14.
Mechanisms of statin-associated skeletal muscle-associated symptoms.
Pharmacol Res
; 154: 104201, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30877064
15.
Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults.
Br J Clin Pharmacol
; 86(2): 352-361, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31657866
16.
Para-Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells.
Int J Mol Sci
; 21(8)2020 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32325754
17.
[Opioid therapy in patients with liver cirrhosis]. / Therapie mit Opioiden bei Patienten mit Leberzirrhose.
Ther Umsch
; 77(1): 14-19, 2020.
Artigo
em Alemão
| MEDLINE | ID: mdl-32486995
18.
OATP1B3-1B7 (LST-3TM12) Is a Drug Transporter That Affects Endoplasmic Reticulum Access and the Metabolism of Ezetimibe.
Mol Pharmacol
; 96(2): 128-137, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127008
19.
Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions.
Nephrol Dial Transplant
; 34(4): 692-702, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30189012
20.
Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers.
Br J Clin Pharmacol
; 85(3): 626-633, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566757